With deep roots in sports, healthcare, and B2B, Indianapolis marketing agencies offer data-driven campaigns for every industry.
Indianapolis's business landscape is characterized by a dynamic blend of sports, healthcare, and fast-growing B2B sectors. Known for hosting major events–most famously the Indianapolis 500–the city has cultivated a robust sports marketing and sponsorship ecosystem. Beyond athletics, Indianapolis has cultivated a thriving life sciences community and a network of logistics and manufacturing companies that fuel the city’s economic engine.
This diverse industry has created a fertile environment for specialized marketing agencies. Many local firms specialize in B2B marketing, promoting manufacturing services, enterprise software solutions, or niche healthcare products. The city’s concentration of healthcare and medical tech companies has led to a concentration of agencies experienced in compliance, patient engagement, and reputation management. Meanwhile, sports marketing remains a core strength, with many local agencies adept at creating fan-centered campaigns, securing high-profile sponsorships, and leveraging influencer relationships.
In the sports ecosystem, agencies launch large-scale national campaigns around high-profile events like the Indianapolis 500 and Gen Con. Leveraging influencer partnerships, sponsorships, and fan-centric strategies, they boost brand engagement and loyalty by tapping into the city’s strong sports culture.
For the healthcare sector, local firms navigate complex regulations, execute lead generation strategies, secure compliance, and build trust for medical and life sciences brands. They understand the nuances of this highly regulated industry, ensuring campaigns meet strict requirements while still resonating with patients and professionals. On the B2B side, agencies are experts on lead generation, CRM-powered advertising, and content marketing–especially for sectors like manufacturing and enterprise software. By educating prospects and guiding them through lengthy buyer journeys, these agencies deliver measurable ROI with tailored campaigns that drive growth and provide data-backed results.
Partnering with a local agency means leveraging a wealth of expertise in high-stakes, ROI-driven sectors like B2B, healthcare, and sports. Whether you need to navigate complex regulations for a medical product launch or engage passionate sports fans through multi-channel campaigns, these agencies have the proven strategies to deliver meaningful results.
Beyond specialized industry know-how, Indianapolis’s central location and expanding tech scene make it an attractive hub for businesses. A moderate cost of living contributes to competitive pricing without compromising quality, which is why many Fortune 500 companies have offices here. This blend of affordability, skilled talent, and a thriving business community creates a powerful environment for growth.
Headquarters
Carmel, Indiana
Founded
1985
Company Size
46
Coles Marketing is a full-service integrated marketing agency with deep roots in public relations, marketing communications and brand development. A leader in the Central Indiana marketplace for more than 30 years, the firm balances traditional PR/advertising practices with the latest digital tools to help clients find success.Services include website development and enhancement, comprehensive brand strategy, digital outreach including Google AdWords and Analytics, graphic design, copywriting, event planning, app development, PR and advertising across every platform.
Headquarters
Fishers, IN
Founded
2017
Company Size
6
Bright, bold marketing communications for Indiana businesses. Add some Magenta to your marcom.
Headquarters
Indianapolis, Indiana
Founded
2011
Company Size
157
MKR is battle-tested with over a half century of experience. From retail, CPG, healthcare and ticketed entertainment to highly regulated industries, our knowledge runs both deep and wide. Today, that experience is surrounded with visionaries and strategists, armed with a mastery of the ever-evolving technologies that shape omnichannel marketing.
Headquarters
Indianapolis, Indiana
Founded
2014
Company Size
7
Kicks Digital Marketing is a tight knit group of designers, developers, writers, and storytellers, creating digital strategies inspired by creativity. We exist to uplift the people and brands around us. We’re smart, creative, sincere humans devoted to making our corner of the digital world more beautiful, more functional, and leave it inherently better than we found it.
Headquarters
Fishers, Indiana
Founded
2018
Company Size
4
We help small businesses, startups, and nonprofits improve online. Attention Digital is an Indianapolis-based digital marketing agency that delivers custom-tailored, affordable marketing solutions. We offer web design, social media, SEO, graphic design, and other related marketing & design services. #attentionindy 🔥
Headquarters
Indianapolis, Indiana
Founded
2003
Company Size
65
We’re a full-service agency where we believe that what makes you different, uncommon, and one of a kind makes you awesome. Let’s be great together.
Headquarters
Indianapolis, Indiana
Founded
2008
Company Size
19
At Collective Alternative, we live in a constant state of WHY? We're always asking ourselves what we can do to better our clients' experience, improve our services and provide the best solutions for each client we have the privilege of working with. At the core of CA are three things: a love for local business, an emphasis on comprehensive solutions, and a firm belief in strategy. Not only do we serve the Indianapolis market, but we're also proud to be a part of it. We are always inspired by the local businesses we work with and witnessing the impact they have on our local communities. That's why we focus so much on strategy. Each strategy we put together for our clients serves as our baseline and our roadmap to getting them where they want and deserve to be. We focus on providing comprehensive, customized solutions so we can develop a strategy based on their needs, goals, challenges and values. We're a full-service marketing and public relations firm, but we can do it all. From web design and development, to branding and advertising, all the way to market research, we're ready to help you make business personal. Are you in?
Headquarters
Indianapolis, Indiana
Founded
2011
Company Size
5
Boldthink is a team of brand advisors and consultants with deep expertise in brand strategy, brand development, and brand management services. Our experience using consumer insights, data, and quantitative and qualitative research allows us to help companies like yours drive innovation and fuel growth.
Headquarters
Carmel, Indiana
Founded
2015
Company Size
15
PLAID becomes an entity of its own right when disparate horizontal and vertical lines and colors interweave-creating a consistent, classic, yet powerful pattern. Allow PLAID to create this brand statement from your various marketing channels and communication inputs.Ad an advertising and full-service marketing agency, THE PLAID AGENCY provides strategic consulting, marketing plan development and oversight, cross-channel management, digital strategy and tactical project implementation, brand creation, multi-channel content creation, social media composing, and more... let's discuss.
Headquarters
Fishers, Indiana
Founded
2002
Company Size
18
MediaFuel is a digital marketing agency that believes what your promoters are saying about your business can be used to fuel the growth of your organization. With a strategic marketing process and creative thinking, we help brands clarify their message, generate demand, and achieve desired results. We offer a full suite of digital marketing services including marketing strategy, video production, website design, content marketing, search engine optimization, digital advertising, photography, and more.
Headquarters
Indianapolis, IN
Founded
1978
Company Size
76
Hirons has been an established leader in the industry since 1978, making us a trusted, stable and seasoned partner for our clients’ advertising and communications needs. For over 45 years, we have created a wealth of knowledge that has produced outstanding work on a local, national and international scale in a wide variety of industries. In 2024, Hirons received approval to become a WBENC-Certified Women’s Business Enterprise. It’s a natural progression for a company with a history of providing opportunities, mentorship and enthusiastic support for women in business. Hirons provides services in branding, advertising, public relations, digital, government affairs and more. Our strategy to outthink, outwork and outperform drives our abilities to exceed clients' expectations. With a multifaceted team that is uniquely structured and experienced, we focus on offering research-based and results-driven work. Our tagline "Be Bold" encapsulates the best of what our agency does. It serves as a constant reminder to step outside the box and relentlessly challenge our capabilities, resulting in continual agency growth.
Headquarters
Indianapolis, Indiana
Founded
2014
Company Size
3
Indy Digital Marketing Solutions is a local Indianapolis full service online marketing company. We offer PPC, SEO, Social Media Management, Display/Remarketing, Facebook Ads, Blogging, Websites and more.We are accepting new clients. Give us a call to schedule a FREE online analysis!
Headquarters
Indianapolis, IN
Founded
2019
Company Size
5
More than an agency:Oppilo is your full service digital marketing solution provider. Oppilo is more than an agency, we are a business partner.Local Partner:We tell you exactly how you measure up against you local competitors and build custom solutions to win in your market.Transparency:A partner doesn't lie. We provide solutions that work and give you access to your own private dashboard to track results in real time.
Headquarters
Indianapolis, Indiana
Founded
1910
Company Size
205
CVR's mission is building brands that matter with services in marketing, advertising, social media, branding, email, SEO, website content, CRM and more.
Headquarters
Indianapolis, Indiana
Founded
1984
Company Size
45
Borshoff is where proven expertise meets fearless creativity. We’re a truly integrated marketing communications agency, helping brands find and share their voices across all internal and external touchpoints. We have a deep bench of marketers, communicators and creatives who partner with our clients to solve their most complex challenges.Our success is rooted in the diverse backgrounds and specialized expertise of our team, as well as a deep understanding of people, their behaviors, and the things that matter to them. Borshoff has mastered the art of connecting people in meaningful ways over the past 35 years, creating lasting connections between brands and stakeholders to deliver measurable business impact.Borshoff is a nationally certified Women’s Business Enterprise (WBE).
Headquarters
Indianapolis, IN
Founded
1992
Company Size
33
Willow has been making things better for more than 30 years.Our clients turn to us for all the things you would expect from a full-service marketing agency-branding, strategy, graphic design, and web development. But what they've come to learn is that they can also depend on us for the less common services like listening, asking tough questions, giving free advice, and attending to the details not found in the media buy-like branded fingernails and tradeshow selfies. We care enough about your goals to make them our goals and we have fun doing it. We know, it's a little unusual, but you'll get used to it. It's the Willow Way.